Carolina Panthers at Los Angeles Rams: Facts & Trends

  • The Carolina Panthers are 1-4 against the spread line this year.
  • The Los Angeles Rams are 1-4 against the spread this season. 
  • The Panthers are 0-1 against the spread when playing on the road. 
  • The Rams are 0-3 against the spread when playing at their home field. 
  • Carolina is 1-1 against the spread as an underdog.
  • Los Angeles is 1-2 against the spread as a favorite.

The Carolina Panthers (1-4) will take on the Los Angeles Rams (2-3) on Sunday.

The Panthers enter this game having dropped two games in a row. They underwent a number of changes following their Week 1 loss, and will try to turn their season around.

The Rams have underperformed this season, but have the talent to get hot at any moment. LA enters this game as the heavy favorite. 

Kickoff is scheduled for 4:05 PM EST at SoFi Stadium in Los Angeles, CA.

Carolina Panthers at Los Angeles Rams: Game Info & Odds

The Panthers and Rams will square off at SoFi Stadium at 4:05 PM EST on Sunday afternoon. 

Los Angeles is favored by over 10 points, according to the majority of top sportsbooks. The reigning champs still feature plenty of firepower despite their underwhelming 2022 effort. 

But the truth of the matter is that LA has labored against the spread in a major way. That narrative has rung especially true at home, where they are 0-3 against the spread. 

That mark certainly leaves the door open for a Carolina upset. 

However, the Panthers have not been great against the spread either. They are 1-4 against it on the year and 0-1 against it when playing on the road. 

In summary, these are a pair of lousy teams where covering the odds is concerned, so far in 2022. But the Rams are far from a lousy team in terms of pure talent. 

LA expects to win this game handily. But are they worth placing your money on? Check out the Panthers at Rams NFL Picks below.

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Carolina Panthers at Los Angeles Rams: Betting Previews

Betting on Carolina Panthers

The Panthers‘ lone win in 2022 came against the New Orleans Saints in a home affair. Carolina pulled out a 22-12 victory over the Saints to jump into the win column.

Christian McCaffrey unsurprisingly led the charge with 108 rushing yards to pace the offense. His performance offset the shaky effort from QB Baker Mayfield.

The Panthers did a tremendous job of limiting New Orleans in the red zone. They also picked off QB Jameis Winston twice in the attempt to capture momentum. 

That win came on the heels of back-to-back competitive losses. The Panthers were 1-2 after Week 3, and looked like they could be a decent team. 

And then Weeks 4 and 5 happened. 

Carolina lost to the Cardinals 26-16 in Week 4, and to the 49ers 37-15 in Week 5. Both the offense and defense struggled in both games, and it was clear change was needed. 

The Panthers fired head coach Matt Rhule after Week 5. Additionally, a defensive coach was let go, and Baker Mayfield is expected to miss Week 6 with an injury. 

This is going to look like a completely different Panthers squad in Week 6. And perhaps that is for the best. 

On the season, Carolina ranks 24th in points per game and 31st in total yards per game. Defensively, they are 20th in points against per game, and 20th in total yards against per game. 

It will be interesting to see how they fare in LA on the road. Their new changes will either spark new life or set them back further.

Betting on Los Angeles Rams

The Rams enter Week 6 fresh off of a pair of losses in Weeks 4 and 5. One of their main issues as of late has been their offense, notably their offensive line. 

The Rams lost 24-9 against the 49ers in Week 4 and 22-10 against the Cowboys in Week 5. Matthew Stafford was continuously under pressure, and the Rams’ offense has failed to get much of anything going in recent memory. 

Cooper Kupp is still posting big numbers, but he’s been one of the few standouts on the team amid their 2-3 start. 

The Rams are just 29th in points per game, and 26th in total yards per game so far in 2022. Those are shocking rankings considering this team won the Super Bowl a year ago. 

Their lack of a rushing game has been an issue as well, as they rank dead-last in rushing yards per contest.

The Rams’ defense has fared well for the most part. They are 16th in points against per game and 11th in total yards against per game. 

Los Angeles is looking to put their struggles in the past and take care of business on Sunday. Winning the game should not prove to be too difficult, but covering the home spread will be the real challenge.

Injury Report


  • Jeremy Chin was recently placed on the IR due to a hamstring ailment. 
  • Bravvion Roy and Andre Roberts have been injured since mid-September, and their timetables are unclear at the moment.
  • Sam Darnold and Baker Mayfield will miss Week 5’s game, leaving PJ Walker as the starter for Week 6.


  • David Edwards recently entered concussion protocol.
  • Cooper Kupp and Tyler Higbee were recently held out of practice due to precautionary reasons. Both are expected to be fine for Sunday.

Carolina Panthers at Los Angeles Rams: Picks & Predictions

Can the Rams overcome their spread woes and cover? Yes.

The Rams are too good of a team to continue struggling. At some point, this team is going to break out and earn a dominant win. And this seems as good a time as any, given the Panthers’ changes in leadership.

The Pick

Take the Los Angeles Rams with your NFL betting selection. 

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