San Francisco, despite dealing with no shortage of injuries, has won six consecutive games. The 49ers will aim to keep rolling on Thursday in this road affair with Seattle. 

The Seahawks are just 2-3 over the course of their past five games. They have slid backward following their strong start to the year. They will look to turn things around in this contest.

The kick-off is scheduled for 8:15 PM EST on Thursday, December 15th, at Lumen Field in San Francisco, CA.

Overall Game Info & Outlook

  • San Francisco 49ers at Seattle Seahawks
  • The 49ers are 5-0 over their last five games. 
  • The Seahawks are 2-3 over their last five games.
  • Lumen Field, San Francisco, CA
  • The kick-off is scheduled for 8:15 PM EST

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San Francisco 49ers at Seattle Seahawks Betting Preview

San Francisco 49ers Preview

The 49ers are playing an inspired brand of football. Jimmy Garoppolo recently endured an injury, and Trey Lance has missed the whole year. Nevertheless, San Francisco is finding ways to get the job done. 

They most recently defeated the Buccaneers 35-7 in a rout. San Francisco is looking to carry that momentum into this clash with Seattle on Thursday evening. 

  • The San Francisco 49ers are 8-5 against the spread this year.
  • The 49ers are 2-3 ATS when playing on the road. 
  • San Francisco is 7-4 ATS when playing as a favorite.
  • They are 1-3 ATS as an away favorite this season.

The Niners have enjoyed a quality season. That can be said for their overall against the spread mark. With that being said, they are just 2-3 ATS when playing on the road. 

Nevertheless, their 8-5 overall ATS record and 7-4 ATS record as a favorite should not be overlooked. This is a team more than capable of getting the job done. 

However, it will be interesting to see how Brock Purdy fares in his next start. He is considered day-to-day with an oblique/rib injury. If Purdy misses the next game with an injury, San Francisco will be down to their fourth QB of the year. 

But San Francisco is hopeful that he will be alright for this clash with Seattle. 

On the season, the 49ers’ offense is eighth in points per game, 10th in total yards per game, 16th in passing yards per game, and ninth in rushing yards per game. 

Defensively, they are first in points against per game, first in total yards against per game, 12th in passing yards against per game, first in rushing yards against per game, eighth in sacks, and second in interceptions. 

San Francisco’s defense will be the key moving forward. And it will certainly be crucial on Thursday against a strong Seahawks’ offensive attack.

Seattle Seahawks Preview 

The Seahawks were defeated 30-24 by the Panthers in their most recent game. The loss was a brutal one, as Seattle has fallen off since their impressive start to the year, but they can still change the narrative and turn things around by finishing the season on a high note.

And they are preparing to go up against an injury-plagued Niners’ team.

  • The Seattle Seahawks are 6-7 against the spread this year.
  • The Seahawks are 3-3 ATS when playing at their home field. 
  • Seattle is 5-3 ATS when playing as an underdog. 
  • They are 2-0 ATS as a home underdog this season.

Seattle needs to lean on their offense. If they can break through against the Niners’ defense on Thursday, that will go a long way in getting the job done. 

Seattle’s defense has struggled through the season. As a result, Christian McCaffrey and the Niners’ offense may be able to put something together. 

For the Seahawks, their offense ranks sixth in points per game, eighth in total yards per game, eighth in passing yards per game, and 21st in rushing yards per NFL game

Defensively, they are 30th in points against per game, 28th in total yards against per game, 18th in passing yards against per game, 31st in rushing yards against per game, 12th in sacks, and ninth in interceptions. 

The 49ers are still a talented team despite being short-handed. The Seahawks will need all hands on deck in this Thursday Night Football contest. 

Top Sportsbooks Odds

San Francisco 49ers at Seattle Seahawks Odds & Picks

Odds for this Matchup:

San Francisco 49ers-3.5-177O/43.5
Seattle Seahawks+3.5+157U/43.5

The 49ers enter this game as narrow favorites on the road. Going into Seattle and taking care of business is never an easy task. 

But will Seattle be able to hold its own in this one? Or are the Niners destined to win their seventh game in a row?

This matchup has the potential to be extremely exciting. The Seahawks’ offense has surprisingly been impressive so far in 2022. Meanwhile, the Niners’ defense is amongst the best in the NFL. 

And with George Kittle and Christian McCaffrey still available on offense, the Niners will remain confident in themselves.

I don’t expect this game to be a shootout by any means, given San Francisco’s stout defense presence, but the Seahawks will find ways to put a decent amount of points on the board. 

In the end, the 49ers will still be the team to roll with. Go ahead and place your bets on San Francisco -3.5 for Thursday Night Football. 

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