You can find this Conference Championship NFL matchup between the Lions and 49ers on FOX at 6:30 (1/28/24). This NFL matchup will be played at Levi’s Stadium in Santa Clara (CA). The 49ers are set as 7-point favorites at home in this NFC showdown.

Can they pull off a home win and cover the spread? Here is a look at some Lions vs 49ers odds that should help you make winning NFL picks for this game.

Lions vs 49ers Odds

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Overall Game Info & Outlook

  • Detroit Lions at San Francisco 49ers

Detroit Lions vs San Francisco 49ers Betting Preview

Detroit Lions Preview

As they get ready to face the 49ers, the Lions carry in a 12-5 record. Within the NFC-North, they are currently in 1st place and are positioned 3rd in the NFC overall. The Lions have put together an above .500 record versus the spread this season, currently at 13-6. Their average scoring margin for this season is +3.9. The Lions’ offense has performed well in the first half of their games, averaging 14.8 points. Their overall offensive numbers of 27.2 is 5th in the NFL Standings.

The Lions come into the game handing the ball off 29 times per game and are currently 7th in rushing yards. Their average yards per attempt is 4.5. Detroit’s passing offense, heading into this week’s game, holds the 3rd ranking in passing yards. In terms of attempts, they are 10th with an average of 35.6 passes per game. So far in this season, Jared Goff has recorded 30 touchdowns, which places him 4th among quarterbacks. His total passing yards of 4575 also ranks him 2nd at his position. On the defensive front, the Lions currently hold the 13th position in tackles for loss and rank 14th in sacks. Opponents are averaging 23.2 points and 344.6 yards per game against them.

San Francisco 49ers Preview

Taking on the Lions, the 49ers will look to improve on their record of 12-5. This mark has them in 1st in the NFC-West and 1st in the NFC. The 49ers have a 9-8-1 record against the spread this season. So far this season, their average scoring margin is +10.9. The San Francisco offense is currently positioned 3rd in the league, scoring an average of 28.6 points per contest. The 49ers hold the 4th position in the NFL with 138.9 rushing yards per game. This average has come on an average of 29.1 rushing attempts (7th). In this week’s game, San Francisco’s passing game is currently 4th in passing yards.

Additionally, they are 28th in pass attempts, throwing an average of 29.4 passes each game. Against the Lions, Brock Purdy will get the start for the 49ers. Over 16 games, he has completed 69.4% of his passes and holds the 5th position among quarterbacks in passing yards. His passer rating is currently 113.0. So far, the 49ers’ defense has given up an average of 305.4 yards per game and 17.7 points per contest (3rd). Coming into the game, they had allowed a completion percentage of 66.0% and had given up 20 passing touchdowns. Against the run, they are 3rd in the NFL.

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Detroit Lions vs San Francisco 49ers Odds & Picks

Odds for this Matchup:

There will be plenty of NFL at BetUS odds for this matchup, and they are going to go much deeper than simply betting on the spread. You can combine NFL bets in order to put together a solid parlay, and there are times in which those NFL odds work together in a big way.

Recommended Pick: Detroit Lions +7

My pick on the spread is Detroit at +7. I’m expecting the Detroit rushing attack to exploit the weaknesses in San Francisco’s rush defense. My play for this game is Detroit at +7. With the over/under line set at 51, I’m going with the under. So far this season, games involving San Francisco have averaged 46.3 points per game, and I expect this game to stay below 51.

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