This game was recently moved to the Sunday Night Football time slot.

The Chargers are fresh off a victory over the Falcons and have now won four out of their past five games leading into this matchup. Nevertheless, L.A. enters this game listed as a fairly convincing underdog. There is no question that the Chargers feature upset potential. 

The Niners snapped a two-game skid by defeating the Rams in their last matchup. San Francisco comes into the game off the heels of a bye week. The 49ers should be well-rested and ready to roll. 

Kickoff is scheduled for 8:20 AM EST on Sunday, November 13th, 2022, at Levi’s Stadium in San Francisco, CA. Let’s take a look at the odds, betting trends, and predictions for this Sunday Night Football affair.

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Overall Game Info & Outlook

  • Los Angeles Chargers at San Francisco 49ers
  • Levi’s Stadium, San Francisco, CA
  • Sunday, November 13th, 2022
  • Kickoff is scheduled for 8:20 PM EST

Betting Backdrops Per Team

Chargers Overview:

The Chargers are playing an inspired brand of football at the moment. They narrowly defeated the Falcons last weekend, but they will certainly be content to walk away with the win. 

L.A. will look to keep rolling on the road in San Francisco. However, upsetting the odds on the road will be an immense challenge on Sunday.

  • The Los Angeles Chargers are 5-3 against the spread this year.
  • The Chargers are 4-0 against the spread on the road.
  • Los Angeles is 1-0 against the spread when playing as a betting underdog in the 2022 NFL season. 
  • They are 1-0 against the spread as an away underdog this NFL season. 

The Chargers have played well against the spread in 2022. This has been especially apparent when playing on the road, as evidenced by their 4-0 ATS road record. 

L.A.’s defense has let them down throughout the year. But their offense has picked up the slack, which is certainly helpful in terms of covering…and upsetting spreads.

On the season, the Chargers’ offense is ranked 13th in points per game, 11th in total yards per game, sixth in passing yards per NFL game, and 28th in rushing yards per game. 

Defensively, they are 30th in points against per game, 21st in total yards against per game, 14th in passing yards against per game, 29th in rushing yards against per NFL game, 17th in sacks, and 13th in interceptions. 

The Chargers have overcome the odds throughout the season. It should be noted that they had high expectations coming into the year but struggled out of the gate. Nevertheless, they seem to be back on track. 

It will be interesting to see how Los Angeles fares on Sunday night. Their defense will need to find an answer for the dynamic duo of Christian McCaffrey and Deebo Samuel (assuming Samuel plays).

49ers Overview:

The Niners have endured an inconsistent season. They have looked like true Super Bowl contenders at times this season. However, they have also looked underwhelming at other times. 

San Francisco will still be confident in its ability to cover the home spread. But their defense will need to post a tremendous performance against L.A.

  • The San Francisco 49ers are 4-4 against the spread so far this season. 
  • San Francisco is 2-1 against the spread when playing at home. 
  • The 49ers are 3-3 against the spread as a favorite in 2022. 
  • They are 2-0 against the spread as a home favorite this season.

The Niners’ against-the-spread records display their all-around inconsistent season. Their 2-0 home ATS record is encouraging. 

Overall, they are just 3-3 ATS as a favorite and 4-4 ATS overall. The Niners are listed as around 7-point favorites at home. We will see if they can cover the spread. 

On the season, S.F’.s offense is ranked 19th in points per game, 12th in total yards per game, 12th in passing yards per game, and 15th in rushing yards per game. 

Defensively, the Niners are sixth in points against per game, first in total yards against per game, eighth in passing yards against per game, first in rushing yards against per game, fifth in sacks, and 16th in interceptions. 

As aforementioned, Deebo Samuel and Christian McCaffrey project to be a dynamic duo for the 49ers. But Samuel is questionable for Sunday night. 

This game will ultimately be decided by the 49ers’ defense. If they play up to their full capability, San Francisco will likely get the job done. However, if they allow the Chargers’ offense to get going, it could be a long night for the Niners. 

Los Angeles Chargers at San Francisco 49ers: Odds & Picks

Odds for this Matchup:

Los Angeles Chargers+7+255O/45
San Francisco 49ers-7-305U/45

The 49ers are touchdown favorites for this Sunday Night Football affair. Despite being listed as fairly convincing favorites, the Chargers will not lack any confidence heading into this contest.

The over/under is set at 45. The under will likely hit, given San Francisco’s defensive ability.

Which team should you place your money on? Can the Chargers upset the road odds, or will the Niners take care of business?

Justin Herbert is one of the best QBs in the league when at the top of his game, and he is going to keep Los Angeles in this game. Regardless of whether L.A. earns the victory on Sunday, they are going to be in a position to upset the odds. 

They have played well as of late, and San Francisco’s inconsistency will ultimately be their downfall. 

Go ahead and place your money on the Los Angeles Chargers in this Sunday Night Football game.

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