Los Angeles Chargers at Indianapolis Colts Picks & Betting Tips

The Los Angeles Chargers (8-6) play the Indianapolis Colts (4-9-1) on Monday Night Football to round up Week 16 of the 2022 NFL season.

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The Los Angeles Chargers (8-6) play the Indianapolis Colts (4-9-1) on Monday Night Football to round up Week 16 of the 2022 NFL season from Lucas Oil Stadium in Indianapolis, Indiana.

After defeating the Tennessee Titans 17-14 the previous week, the Chargers will try to extend their winning run to three games. As a result of their 39-36 loss to the Minnesota Vikings last week, the Colts are currently in the middle of a four-game losing skid.

The last time these two matched up against each other was back in 2019, when the Chargers grabbed the victory by a score of 30-24. There is plenty at stake in this matchup; the Chargers will be looking to clinch a spot in the AFC playoffs, while the Colts will be looking to rebound from arguably the most embarrassing loss of the year. Let’s take a closer look at the best Chargers vs Colts betting picks.

Overall Game Info & Outlook

  • Los Angeles Chargers (8-6) vs. Indianapolis Colts (4-9-1)
  • In Week 15, the Chargers beat the Titans 17-14, while the Colts were defeated by the Vikings 39-36
  • Game Day: Monday, December 26, 2022
  • Game Time: 8:15 PM ET
  • TV Channel: ESPN
  • Location: Indianapolis, Indiana
  • Stadium: Lucas Oil Stadium

Los Angeles Chargers at Indianapolis Colts Betting Preview

Los Angeles Chargers Preview

The Chargers have come on strong as of late, winning three of their last four contests. In their thrilling Week 15 win over the Titans, the Chargers kicked a 43-yard field goal with four seconds remaining in the game.

Although they have covered the spread just once in their last four contests, the Chargers have a two-game winning streak and can clinch an AFC playoff spot with a victory over the Colts.

Justin Herbert and the Chargers have come on strong in pursuit of the playoffs. Herbert has thrown for five touchdowns and two interceptions over the last four weeks surpassing the 300-yard mark in three straight games. Expect a heavy dose of passes as the Chargers are scoring 22.4 points over their last five contests.

  • The Chargers are 8-5-1 ATS this year. 
  • Los Angeles is 1-2-1 over their last four games. 
  • The Chargers have gone under the total in their last three games and five of their last seven overall. 
  • Los Angeles has covered the spread in five of their last seven road contests. 

In order to win this matchup, the Chargers will have to play strong football on both sides of the ball. Look for Los Angeles to utilize Justin Herbert and Austin Ekeler throughout the game.

The Colts were torched for 460 yards and four touchdowns through the air while also allowing 190 total yards to Dalvin Cook. Expect Herbert and Ekeler to connect several times to keep the Colts’ defense off balance.

On defense, the Chargers will be tasked with holding a Colts team that scored 36 points last week. Despite conceding 24.3 points per game, the Chargers have held opponents to 15.5 points over their last two contests. They will need another strong performance from that defensive unit to secure a spot in the AFC playoffs.

Indianapolis Colts Preview

The Colts have had a pretty disastrous season. Not only have they been eliminated from the playoffs and hired an inexperienced head coach, but they also blew the biggest lead in NFL history. After jumping out to a 33-0 halftime lead against the Vikings last week, Indianapolis was outscored 39-3 in the second half and overtime. 

To make matters worse for the Colts, they are benching Matt Ryan for the second time this year and turning to Nick Foles, who has not started a game all season. The offensive unit ranks 24th in the league averaging 319.6 yards per game, while the defense comes in at 12th, surrendering 329.3 yards per contest.

  • The Colts are 6-8 ATS this year. 
  • The Colts are 3-5 ATS over their last eight games. 
  • The Colts have gone over the total in four of their last five games. 
  • Indianapolis is 2-12 ATS over their last 14 contests at home against the Chargers.

The Chargers are in a great spot to pick up the win on Monday Night Football. The Colts are coming off one of the most demoralizing losses of the season. Additionally, Indianapolis is rolling with a veteran quarterback who hasn’t attempted a pass all season.

The Chargers, on the other hand, have started to pick up their play, winning three of their last four contests. In addition, the Chargers can earn a playoff spot with the win and are 5-2 over their last seven road matchups.

Top Sportsbooks Odds

Los Angeles Chargers at Indianapolis Colts Odds & Picks

Odds for this Matchup:

 SpreadTotal (O/U)Moneyline
Chargers-4.5 (-110)O45.5 (-110)-210
Colts+4.5 (-110)U45.5 (-110)+170

Despite having a 4-9-1 record, Indianapolis frequently manages to stay in games. Indy’s defense often keeps the squad in the game giving the offense a chance.

The Chargers do, however, appear to only compete in close contests. Los Angeles is prone to one-possession games, win or lose, giving the Colts an opportunity to win this game.

It’s interesting to note that the Chargers’ eight victories have all been decided by a one-possession game. With a postseason berth on the line, the Chargers have more to play for, but 4.5 points are too much for them to cover. Looking at the NFL odds, the best way to go about this game is to back Indianapolis to keep this game within the 4.5-point spread.

When making your NFL picks and predictions, place a bet on Indianapolis Colts +4.5 at -110.

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