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Buffalo Bills Betting Odds

You can bet on Buffalo Bills with confidence and security at any of the Online Sportsbooks we have detailed selected for you, including the best NFL odds, NFL moneylines, spreads, Over/Under totals, and a ton of NFL prop odds.

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Buffalo Bills 2021 Schedule

The breakdown for all NFL teams can be found on OBS: Online Betting Sports, as we take a look at Buffalo Bills 2021 schedule:

WeekDateOpponent
Week 1Sept. 12vs. Pittsburgh
Week 2Sept. 19at Miami
Week 3Sept. 26vs. Washington
Week 4Oct. 3vs. Houston
Week 5Oct. 10at Kansas City
Week 6Oct. 18at Tennessee
Week 7Oct. 24BYE
Week 8Oct. 31vs. Miami
Week 9Nov. 7at Jacksonville
Week 10Nov. 14at New York Jets
Week 11Nov. 21vs. Indianapolis
Week 12Nov. 25at New Orleans
Week 13Dec. 6vs. New England
Week 14Dec. 12at Tampa Bay
Week 15Dec. 19vs. Carolina
Week 16Dec. 26at New England
Week 17Jan. 2vs. Atlanta
Week 18Jan. 9vs. New York Jets

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