The Minnesota Twins (43-36), riding a hot streak, head to Chase Field in Phoenix to take on the Arizona Diamondbacks (39-40) in an interleague MLB game on Wednesday night. The Twins look to extend their winning streak, while the Diamondbacks aim to even the series after a close loss in Minnesota on Tuesday.

  • Minnesota Favored on the Road: The Twins (43-36) travel to Chase Field to face the Diamondbacks (39-40) looking to extend their winning streak.
  • Pitching Matchup: Simeon Woods Richardson gets the nod for Minnesota against Ryne Nelson for the Diamondbacks.
  • Betting Lines: The Twins are favored on the money line (-119) with the over/under set at 9 runs. First pitch at 9:40 PM ET (ESPN+).

Here is a look at some Twins vs Diamondbacks betting analysis that should help you make winnings MLB picks for this game.

Twins vs Diamondbacks Odds

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Explore Twins vs Diamondbacks Betting Picks on legal online sports betting platforms.

Overall Game Info & Outlook

  • Minnesota Twins at Arizona Diamondbacks
  • The Twins come into this matchup with an overall record of 43-36.
  • The Diamondbacks come into this matchup with an overall record of 39-40 in the MLB Standings.

Minnesota Twins at Arizona Diamondbacks Betting Preview

  • Diamondbacks Triumph: Arizona edges Minnesota 5-4 in a thrilling back-and-forth game.
  • Marte and Carroll Lead the Charge: Ketel Marte and Corbin Carroll spark the offense with two hits and a run each for the Diamondbacks.
  • Twins Rally Falls Short: Minnesota mounts a late comeback with three runs in the 7th but falls short. Ryan Jeffers homers for the Twins.

Twins Aim to Bounce Back After Series Opener Loss to Diamondbacks

  • Chasing the Leaders: Minnesota (43-36) looks to close the gap on the AL Central-leading Guardians (9-game lead in the MLB Stats) with a win in Arizona.
  • Solid Road Record: The Twins boast a strong road record (.500) and are 20-20 as the road favorite.
  • Run Line Success: Minnesota has been a reliable run line team (35-44), especially on the road (20-20).
  • Can They Overcome Recent Struggles? Despite a winning overall record, the Twins have lost four of their last six games and will look to turn things around.

Diamondbacks Aim for Upset Against Twins After Series Opener Win

  • Hot at Home: Arizona (39-40) looks to build on their two-game home winning streak against the Twins.
  • Divisional Race Heating Up: The Diamondbacks sit 3rd in the NL West, just 1.5 games behind the Padres for 2nd place.
  • Can They Keep It Going? Arizona has been a strong run line team (38-41), especially on the road (21-20).
  • High-Scoring Affair Possible? Diamondbacks games average 9.5 runs, with a slight over/under split despite today’s line being set at 9 runs.

Recommended Pick: Diamondbacks ML +101

Our pick for this Twins vs. Diamondbacks matchup is to take the Diamondbacks on the money line at +101. We have the Diamondbacks winning this one by a score of 6-5. At +101, the Diamondbacks are offering a solid payout for a team that we have winning this matchup.

Looking at the starting pitchers, we have Ryne Nelson finishing with five strikeouts compared to Simeon Woods Richardson with four. Nelson is projected to finish with a higher ERA than Richardson, but we have Nelson finishing with a win compared to Richardson.

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